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Tuesday, August 20, 2013
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Wednesday, March 20, 2013
Sleep study reveals how the adolescent brain makes the transition to mature thinking
Mar. 18, 2013 ? A new study conducted by monitoring the brain waves of sleeping adolescents has found that remarkable changes occur in the brain as it prunes away neuronal connections and makes the major transition from childhood to adulthood.
"We've provided the first long-term, longitudinal description of developmental changes that take place in the brains of youngsters as they sleep," said Irwin Feinberg, professor emeritus of psychiatry and behavioral sciences and director of the UC Davis Sleep Laboratory. "Our outcome confirms that the brain goes through a remarkable amount of reorganization during puberty that is necessary for complex thinking."
The research, published in the February 15 issue of American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, also confirms that electroencephalogram, or EEG, is a powerful tool for tracking brain changes during different phases of life, and that it could potentially be used to help diagnose age-related mental illnesses. It is the final component in a three-part series of studies carried out over 10 years and involving more than 3,500 all-night EEG recordings. The data provide an overall picture of the brain's electrical behavior during the first two decades of life.
Feinberg explained that scientists have generally assumed that a vast number of synapses are needed early in life to recover from injury and adapt to changing environments. These multiple connections, however, impair the efficient problem solving and logical thinking required later in life. His study is the first to show how this shift can be detected by measuring the brain's electrical activity in the same children over the course of time.
Two earlier studies by Feinberg and his colleagues showed that EEG fluctuations during the deepest (delta or slow wave) phase of sleep, when the brain is most recuperative, consistently declined for 9- to 18-year-olds. The most rapid decline occurred between the ages of 12 and 16-1/2. This led the team to conclude that the streamlining of brain activity -- or "neuronal pruning" -- required for adult cognition occurs together with the timing of reproductive maturity.
Questions remained, though, about electrical activity patterns in the brains of younger children.
For the current study, Feinberg and his research team monitored 28 healthy, sleeping children between the ages of 6 and 10 for two nights every six months. The new findings show that synaptic density in the cerebral cortex reaches its peak at age 8 and then begins a slow decline. The recent findings also confirm that the period of greatest and most accelerated decline occurs between the ages of 12 and 16-1/2 years, at which point the drop markedly slows.
"Discovering that such extensive neuronal remodeling occurs within this 4-1/2 year timeframe during late adolescence and the early teen years confirms our view that the sleep EEG indexes a crucial aspect of the timing of brain development," said Feinberg.
The latest study also confirms that EEG sleep analysis is a powerful approach for evaluating adolescent brain maturation, according to Feinberg. Besides being a relatively simple, accessible technology for measuring the brain's electrical activity, it is more accurate than more cumbersome and expensive options.
"Structural MRI, for instance, has not been able to identify the adolescent accelerations and decelerations that are easily and reliably captured by sleep EEG," said Feinberg. "We hope our data can aid the search for the unknown genetic and hormonal biomarkers that drive those fluctuations. Our data also provide a baseline for seeking errors in brain development that signify the onset of diseases such as schizophrenia, which typically first become apparent during adolescence. Once these underlying processes have been identified, it may become possible to influence adolescent brain changes in ways that promote normal development and correct emerging abnormalities."
Feinberg's study, which was funded by the U.S. Public Health Service (grant R01MH062521), was co-authored by Ian Campbell, a project scientist with the UC Davis Department of Psychiatry and Behavioral Sciences.
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The above story is reprinted from materials provided by University of California - Davis Health System.
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Journal Reference:
- I. Feinberg, I. G. Campbell. Longitudinal sleep EEG trajectories indicate complex patterns of adolescent brain maturation. AJP: Regulatory, Integrative and Comparative Physiology, 2012; 304 (4): R296 DOI: 10.1152/ajpregu.00422.2012
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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/9nmgCjKwbxw/130319102757.htm
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desire to inspire - desiretoinspire.net - Monday's pets on furniture
If you'd like to send me photos to include in next week's "pets on furniture" post, please ensure your photos follow my basic rules: First, the pet must be on a piece of furniture. And?said piece of furniture must be clearly visible in the photo, so it takes center stage rather than your pet.?Think of it more of a photo of a great piece of furniture that you want to show off...and your pet happens to be sitting on it. And second, the photo must be of?decent quality.?If it's dark or fuzzy then it may not make the cut. Photos, your name, location and a brief description can be sent to desiretoinspirekim@hotmail.com and?PLEASE don't send closeups of your pet!?Thanks!
This is Rita from Milan,Italy. She is on her favorite place: the rocking chair.
- Valeria
This is my dog Choco. they say beagles are natures bed warmers - i think its true.
- Leah (Newcastle, Australia)
I obsessed about getting this beautiful (huge) chair in my kitchen?it's become Ginger's favorite spot.
- Meghan (Catskills, NY)
this is Nanook and Blu on my couch.
- Rob
this is Lolav my little dog, she's the princess of the house and she loves the white couch and the owl's cushions are their friends.
- Victoria (Mar del Plata, Argentina)
Quim, when he was 6 month old on the couch. As always?
- Paula
usually my maine coon is not allowed to climb on the table,but i didn't scold her that time,cause it's time to pose for a pic!!!
- Sophie (Paris)
On a partially related note, it seems I've got a new visitor stopping by pretty regularly to check what's on the menu. Yesterday it was a fresh chicken carcass. We figured it was easier to just give up the chicken instead of ending up with the contents of our garbage cans stewn all over the backyard. I think we're going to call him/her Zorro.?
Source: http://www.desiretoinspire.net/blog/2013/3/18/mondays-pets-on-furniture.html
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Tuesday, March 19, 2013
Brian Murphy: Boise State hoping to make NCAA Tournament memories
Boise State's Ryan Watkins (0) and Thomas Bropleh, right, celebrates a 3-pointer by Anthony Drmic, left, against Air Force during their game Feb. 20 at Taco Bell Arena. Boise State won 77-65.
Joe Jaszewski ? jjaszewski@idahostatesman.com
For Boise State junior Thomas Bropleh, it is Carmelo Anthony's run to the NCAA title as a Syracuse freshman in 2003.
For Bropleh's teammate and classmate Ryan Watkins, it is Kemba Walker carrying Connecticut to the 2011 championship.
Those are their favorite NCAA moments.
For now.
The Broncos - Bropleh and Watkins and all the rest - could very well have their own tournament memories at this time next week.
Boise State will find out its NCAA Tournament fate Sunday evening. Most mock brackets place the Broncos in the 68-team field. The team will be watching nervously together as the brackets are unveiled.
"Praying and going to church on Sunday," junior guard Jeff Elorriaga said. "It's something every college in America wants - to play in the NCAA Tournament. Hopefully we get there."
The Broncos have reached the tournament five times, the last in 2008. All came as an automatic qualifier for winning the conference tournament.
So Boise State has never had to sweat out the bubble. Never had to face Selection Sunday knowing it could bring ultimate elation or real dejection. Never had to wait it out with hearts beating faster and faster as CBS drags out its show, its talking heads gabbing and cutting to commercial.
"It'd be unbelievable. Growing up as a kid and seeing all those moments," said Bropleh, who wasn't even a teenager when Anthony and the Orange had their one shining moment. "It would be unbelievable just to be in the tournament."
No current player has ever laced it up in the tournament. Bropleh, Elorriaga and Watkins were on the 2010-11 squad that reached the WAC Tournament championship game in coach Leon Rice's first year. The Broncos fell to Utah State.
Watkins, then a freshman, didn't realize at the time how hard it would be to get back in that position. Now - after a move to the rough-and-tumble Mountain West and last year's 13-17 struggle - the Broncos' starting center has a much better appreciation.
"I know how hard it is to get there. It's tough to get there," Watkins said. "It would be amazing."
Tough is a good way to describe the past few days for the Broncos, who lost to San Diego State on Wednesday in the quarterfinals of the Mountain West Tournament. They've gone from out to in on many brackets as the rest of the bubble teams (it is a very weak bubble year) lost in their conference tournaments.
Will four wins against top-50 teams be enough? Will an 8-8 record against top-100 teams be enough? Will having a winning record in the No. 1-ranked conference in the country be enough?
"We did all that we could," Rice said. "Did you go out and schedule? Did you go out and play a lot of high-level teams? ... What the committee wants you to do is play a lot of good teams, not dodge teams."
The only opinions that matter now are those of the 10 members on the selection committee. And the only thing Boise State players can do is wait and pray and hope and sweat and dream.
Wait for the brackets.
Pray to see their name.
Hope to make their own memories.
Sweat. Just sweat.
And dream. Dream of playing on the same stage Carmelo and Kemba once did. Dream of actually doing what every college basketball player dreams about. Dream of making their own moments.
Brian Murphy: 377-6444, Twitter: @MurphsTurph
The Race to Cash in on Earth Orbit
The 165-foot-tall rocket parts the air in front of its tip with a violent ripping sound; a setting sun gives its billowing trail of smoke a lustrous orange fringe. Mowry, president of the U.S. subsidiary of the European launch company Arianespace, cranes his head to watch the rocket soar from this equatorial spaceport, located on the northeastern coast of South America. But his attention is divided between the rocket and his customer, communications mogul Charlie Ergen. The co-founder of Dish Network is standing nearby, flanked by his wife and three of their children, all turning their heads in unison to watch the launch vehicle streak over the Atlantic. It's an oddly intimate family moment.
Ergen, No. 106 on Forbes's list of global billionaires, is famous for being a former professional poker player as well as serving as chairman of Dish Network and EchoStar. His face is surprisingly calm considering what's at stake: It's his $250 million satellite that's being violently blasted out of Earth's gravity well, loaded in the tip of a rocket that cost him another $270 million. The only hint of nerves during this July launch is found in his sandals?Ergen repeatedly transfers weight from one foot to the other.
The primary payload for this launch is the 13,500-pound EchoStar 17, one of the biggest communications sats ever built. (A small European weather sat is sharing the ride.) When placed in geosynchronous orbit?where the satellite can remain in position over one spot on Earth?EchoStar 17 will direct 60 beams that deliver download speeds of more than 100 gigabits per second to millions of Ergen's customers across half of the continental United States. The satellite should recoup the cost of manufacture and launch in just a few months.
Mowry's company is playing a longer game, for even higher stakes. A crash, a delay, or incorrect orbital placement would result in cancellations, design reviews, and lost orders. And these days there is plenty of competition. Ergen is known to shop for launch providers: He's hired Russian, Chinese, and Swiss firms to loft his communications birds. For Mowry, a routine launch is engineering nirvana. "We love the word nominal," he says after hearing a positive report from mission control.
The rocket shrinks in the sky from a gleaming white tube to a pinprick of light 40 miles high. Under binoculars, the single bright point divides into three. Twin dying embers fall away from the still-bright central speck?the empty solid-fuel boosters have detached. Moments later the clear weather enables the rarest spectacle of a launch: The light divides again as the fairing at the rocket's tip that houses the payload opens and falls away in a short-lived glimmer. "That's great, it's really rare to see that," Mowry says, grinning.
But Ergen does not smile. The safety of his sat is not ensured until it separates from the rocket's upper-stage payload bay. Viewers turn their attention to TV screens mounted at the viewing platform. Twenty tense minutes pass; Mowry fills the time by explaining to Ergen's daughter's boyfriend how Earth's spin at the equator helps boost hundreds of extra payload pounds into orbit.
At 27 minutes, word comes in: About 600 miles up, a little north of Australia, a clamp band opens, and springs around the upper ring push the satellite away from the adapter. Sat sep is confirmed. "Good job, boys," Ergen says, clapping. Then he reins it in. There is another team nearby waiting to hear if their weather satellite is safely away. Minutes later its release is confirmed, and the celebration begins.
That evening's party at the Ergens' hotel in Kourou includes carved meats, rum, seafood, fine wine, and, after dessert, Cuban cigars on the beach deck. Ergen talks about his family roots in Oak Ridge, Tenn., and receives reports on his satellite's health.
This is Arianespace's 49th consecutive successful Ariane 5 launch, and this reliability has made the company a powerhouse in the increasingly competitive space industry. An all-expenses-paid spaceport, government-supported insurance, and infusions of cash from a score of European nations help too. Arianespace gets $130 million a year from the European Space Agency (ESA) just to balance its books.
Most Americans don't know it, but the majority of the satellite services they enjoy use hardware lofted by European Union rockets. (The big exception is GPS, which is operated by the U.S. Air Force.) Nearly half of American-owned commercial satellites are launched from the EU spaceport in Kourou.
French Guiana's isolated jungle spaceport is not the only place where nations launch private-sector sats. Russia and China offer their services on the open market, and government-backed newcomers in Japan and India promise more competition ahead.
But in the U.S. something different is happening: Private companies, lightly subsidized by the U.S. government but operating on their own, are entering the commercial launch industry. If these U.S. upstarts succeed, they could drive prices down and use Earth's orbit to connect remote areas, empower personal electronics, and create high-tech jobs.
This is the 21st century's space race?one you've probably never heard of.